Historian Kenneth Stampp makes an interesting point about differing locations of slaves determining the destination of escapees. Those living near Indians might, for example, seek refuge with local tribes, as was the case in Florida.
“…Florida slaves escaped to the Seminole Indians, aided them in their wars against the whites, and accompanied them when they moved to the West. At Key West, in 1858, a dozen slaves stole a small boat and successfully navigated it to freedom in the Bahamas. Arkansas runaways often tried to make their way to the Indian country.” (Stampp, 120)
Those nearer to the north often choose to escape to the north where there was a greater presence of abolitionists.
Those in Texas would escape in larger numbers to Mexico.
“In Mexico the fugitives generally were welcomed and protected and in some cases sympathetic peons guided them in their flight.” (Stampp, 120)
Kenneth M. Stampp, The Peculiar Institution: Slavery in the Ante-Bellum South